Everything You Need to Know About SARMs – Types, How Do They Work, Where Can You Find Them?
Recently, the use of Selective Androgen Receptor Modulators (SARMs) has grown in professional bodybuilders and athletes who are using them just like they did with anabolic steroids. But are SARMs safer than the anabolic steroids or is it just a myth we are revolving around?
People are using SARMs only because of their selective nature.
It is the very formula of different SARMs that particularly targets a single receptor, leading to results like muscle mass gain, fat loss, increased basal metabolic rate, nitric oxide boost, and testosterone elevation, etc., all come separated.
In this very case, chances of side effects like prostate enlargement, liver toxicity, and renal failure are very less. But beware for SARMs is also the androgenic compound with so little information available about them. 
Many Pharmaceutical’s research departments are still carrying the studies related to SARMs and their exact mechanism which can decipher many things that are still locked, and it’s growing by every year!
To understand the very nature of SARMs collectively, you must know every compound in-depth.
For this, we have extensive knowledge about the SARMs compound given right below. But first, let us describe SARMs all in one.
SARMs – What Are They?
SARMs are Selective Androgen Receptor Modulators which is currently considered safer and less toxic than anabolic steroids.
Type wise, SARMs fall into 2 main categories, one that is STEROIDAL and the 2nd one is NON-STEROIDALS.
- STEROIDAL SARMs were discovered about 70 years ago with no use for human conditions except those with dire needs. These SARMs are also considered long-gone for now.
- STEROIDAL SARMs are the ones which bind to the animal and human receptors, especially in the bones and muscle receptor where they create the anabolic effect afterward.
SARMs Types, Benefits and Half-Life
There are many types of SARMs, some are related to the exact category of SARMs while others only share a very common mechanism.
Overall, we will describe 8-9 types of SARMs that are currently in for the use of performance enhancement and other multiple reasons.
These compounds related to SARMs are proving to be a powerful alternative to anabolic steroids in many states.
Those SARMs used by the bodybuilders are athletes currently are:
- Testolone (RAD-140)
- Cardarine (GW-501516)
- Ligandrol (LGD-4033)
- Ostarine (MK-2866)
- Andarine (S4)
- Myostatin (YK-11)
- GTX S-23
- Nutrobal (MK-677)
- Stenabolic (SR-9009)
SARMs detailed review will help you know the difference between their types and helps you choose the right one for you. 
There are places where you can buy SARMs at a cost-effective price and those are 100% real SARMs.
Also known as RAD-140 from their chemical structure, Testolone is one of the most powerful SARM available today.
Testolone can affect the mass gain even in smaller doses and build enormous body shape in no time.
The company behind the manufacturing of Testolone SARM is Radius Health which is formulating this for medical conditions like:
- Breast Cancer
- Muscle Wasting Disease
- Alternative to Testosterone Replacement Therapy (TRT)
The mechanism of RAD-140 states the targeting of skeletal tissue androgen receptors and which promotes the generation of lean muscle mass.
Testolone is also considered the purest of all SARM despite its potency being 10% that of testosterone.
Testoline Half-Life: 20-24 Hours
2) Cardarine (GW-501516)
At first, Cardarine was designed for treating certain cardiovascular diseases and other medical conditions such as Type II Diabetes, Obesity and other metabolic disorders.
Use of Cardarine is heavily associated with reducing the level of Cholesterol for which it is offered for the athletes for maximum performance.
Cardarine is partly SARM and part of it belongs to PPAR class. These are Peroxisome Proliferator-Activated Receptor Agonist, which are different from SARMS.
They do not bind with androgen receptors nor creates any anabolic effects, while the testosterone level remains untouched when using Cardarine and certain types of PPARs. The only use of them is to treat metabolic syndromes and binding with the blood sugar and triglycerides.
When you think about the muscle-building SARMs, Cardarine is not the one which shines most beautifully.
Yes, for the performance-enhancing objectives, there is nothing better than Cardarine and its precursors.
Cardarine Half-Life: 16-24 Hours
3) Ligandrol (LGD-4033)
Ligandrol is the type of SARMs men are using for excessive mass gain and bulk size gains.
Under human clinical trials, Ligandrol was found out to be the most intimidating muscle building SARM which increases bulk without increasing fat.
This makes it less or no toxic to the cardiovascular health which works positively.
Much of the studies done on Ligandrol are focusing on its potential use against age relayed muscle-wasting disease, cancer, and osteoporosis where the use of LGD-4033 might play an important role but who knows.
Ligandrol Half-Life: 24-36 Hours
4) Ostarine (MK-2866)
Ostarine, like other SARMs, is the research chemical that is currently designed for treating osteoporosis and muscle wasting disease.
It is known by many names like Ostabolic, Enobosarm but we would just stick with the MK-2866.
The use of Ostarine is catchy for many athletes since the compound focuses mainly on performance enhancement and induces the anti-catabolic state in the human body.
This is where your body doesn’t lose any lean muscle mass and this is one of the greatest effects on Ostarine.
Ostarine like all SARMs binds to the selective androgen receptors located in muscles and bone tissues. It is the ideal SARM for muscle mass gain and fat reduction, while the mass gaining effects are potentially larger than those of Anabolic Steroids.
It offers relief from the side effects of anabolic steroids with the same type of results appearing in a short time.
Ostarine Half-Life: 24 Hours
5) Andarine (S4)
Andarine has been used by numerous athletes world-wide for multiple objectives.
You can say about this SARM that it is a mystery to many experts since the compound is not under research and, to be honest, many publications about it weren’t even published.
Nevertheless, Andarine exerts the strongest anabolic and androgenic effects.
Andarine Half-Life: 3-4 Hours
6) YK-11 (Myostatin)
Myostatin is the strongest SARM available to you now these days, some people believe it is the closest you can get to the anabolic steroids where it’s not the real steroid!
YK-11 is a steroidal SARM that was designed to modulate the DHT hormone, this effect is like the effect of anabolic steroids and for this Myostatin considered is the closest to the anabolic steroids.
Like many other SARMs available in our list, YK-11 is banned by the Doping Agencies for being Performance Enhancing Drugs.
By this notion, you can guess how many athletes’ advantages are inside in this particular SARM.
The mechanism of YK11 is binding with the androgen receptors in muscle and bone while prostate health won’t be affected.
YK-11 Half-Life: 6-8 Hours
7) Nutrobal (MK-677)
Nutrobal is not a SARM but a Ghrelin Receptor Non-Peptide Agonist, which works somehow like SARMs.
Like SARMs, the Nutrobal acts only one selective receptor which then induces further biochemical reactions.
The main thing about Nutrobal can replicate the activation of Growth Hormone which leads to the secretion of HGH and Insulin-like Growth Factor (IGF-1). This makes it useful for the bulking cycle.
The effect of Nutrobal i.e. production of HGH and IGF-1 makes it the best choice for bodybuilders because this is what their demands, excessive muscle mass, and overall body growth.
MK-677 is also supportive of the building of lean muscle mass without increasing fat mass. Humans experienced certain other effects with Nutrobal apart from increased muscle mass; these are enhanced bone mineral density and strength gains.
Nutrobal Half-Life: 24 Hours
8) Stenabolic (SR9009)
Stenabolic is only undergoing multiple pieces of research in animals where it leads to endurance enhancement, reduction of cholesterol, anxiety, inflammation, and weight.
When these effects are converted to human, it strikes a charm for many athletes for their boosted endurance and utmost body performance.
Circadian rhythm is how the human body functions throughout the 24-hours cycle period, both day and night. Stenabolic was created to study this rhythm which is remarkable for athletes to improve their endurance level and energy.
These come after the potential use of blood glucose and fats which by the use of SR9009 comes to boosting the performance and power to the body core.
This will lead to drastic performance enhancement to achieve super goals rapidly.
Stenabolic Half-Life: 4 Hours
How Selective Androgen Receptor Modulator Work?
SARMs works by targeting the androgen receptors located in different parts of the body. The effect is selective because of which SARMs are extremely valuable for treating certain types of medical conditions.
SARMs also help to eradicate the side effects in other parts of the body which are not induced by the SARMs compounds.
It is the reason SARMs are designed to exert the same effect as anabolic steroids without the side effects, these are more enhanced form of specific tissues targeted than Testosterone based hormonal replacement therapy.
The main purpose of SARMs is mentioned above, but currently, they are still under development.
This will be quite not being the 100% selective with 0 chances of tissues impact on the non-targeted area. This means SARMs delivers its results with the side effects that are androgenic and centered on the male prostate.
Are SARMs Legal?
In the US and other countries of the world, SARMs are not approved for human use.
Their development began in 1990 where they addressed some medical concerns like post-cancer muscle recovery to which SARMs were effective. Still, SARMs are not passing through much of clinical trials since many Pharmaceutical companies stopped their development.
Seller of the SARMs sometimes has to pay higher penalties where they try to sell these compounds with the label “For Research Purpose Only” at the back of the bottle.
Some sellers will not mention the list of ingredients that are not considered legal either; these individuals are found guilty of breaking the law and charged with felonies.
Athletes around the world who tried SARMs and their blood test showed the positives were disqualified from the games, this shows they are being treated as they will after using anabolic steroids. But still, at this time, SARMs are available at many online stores claiming to sell the 100% pure compound.
Although the highest purity of the SARMs is very unlikely to be available and is nearly impossible to get a pure form of SARM with such unapproved local products,
What Are SARMs Benefits?
It is noted that most SARMs provides the same kind of benefits as Legal Steroids.
- Enhanced Endurance and Stamina
- Increased Muscle Mass
- Fat Reduction
- Improved Muscle and Bone Density
- Preservation of Lean Mass
Other benefits of SARMs involved the absence of major side effects caused by the anabolic steroids.
These side effects can destroy your years of hard work and minimize the gender capability in some men like Gynecomastia which is a development of boobs on a man’s chest, Water retention which gives them bloated looks.
All these side effects are due to the Aromatization and rise of the estrogen level.
SARMS Supplements (Types and Doses)
About SARMs Dosage Forms, Which One is Better? Liquid or Capsule
Even if you are planning to buy SARMs from reliable sources and use it, you will have to choose between the 2 dosage forms. These are:
When you look at their chemical state, they are the same. But the Liquid form of SARMs is raw or you can say CONCENTRATED than the capsules.
SARMs in capsule form is the result of the manufacturing process which can be known to anyone and is quite easy to use.
So it’s up to you whether you like the confusing liquid SARMs taken through injection or the simply engulf-able capsules.
The selection of liquid vs capsule SARMs also depends on the place from where you have purchased them.
Also their legitimate status and how they are referring you to use them. The liquid and capsule forms of SARMs are two honest preparations, but there is also another form that is included in some bodybuilding supplements.
This can be another feasible way for the public to use SARMs most conventionally, since the capsules.
SARMs Vs Anabolic Steroids & Prohormones
In the world of Performance Enhancing Substances, there are many options available, but the well-known ones are 3.
- Anabolic Steroids
While comparing the three main performances enhancing compounds, we found that the majority of people don’t care about which one is the best. But for the record, when you differentiate between them in terms of efficacy, you will find the best solution for increasing your body growth.
First of all, SARMs are quite different and safer than anabolic steroids because of their selective androgen receptor targeting nature.
They do not come with the prostate enlargement side effect, or in females, it’s Virilization which is mainly caused by the use of Anabolic Steroids which promotes Testosterone in females.
SARMs are better than Anabolic steroids because it doesn’t convert into DHT or Estrogen since it also binds with the androgen receptor.
This way you are not going to experience feminine side effects with SARMs that are:
- Breast Enlargement in Men (Gynecomastia)
- Water Retention
Now, about Prohormones, They react in the human body same as anabolic steroids, with the same latitude of benefits and side effects. This makes both Anabolic steroids and Prohormones the same and SARMs better than BOTH OF THEM!
Stacking Up SARMs – Which SARMs Stack is the Best?
It is possible to stack up multiple SARMs, but for your safety, the best use of SARMs at the start is by using a single compound first.
Stacking up SARMs is not recommended for the beginners since they don’t know much about which SARMs is causing which side effects (as multiple SARMs are being used at once). This will also eliminate the know-how about the precise effect of a particular SARM.
If you have been using a single SARM compound for some time and now you want to bring a change. Well, the use of SARMs stack can yield the extra benefits but do you know about the stacking of SARMs?
Like steroid stacks, the idea of forming SARMs Stack depends on your fitness goals. Whether you are leaning towards the bulking phase or the cutting, it could even be for the strength we don’t know, but what we know is that you are going to get the benefits in triple form.
There are two main stacks that SARMs users should aim for. These are:
1) SARMs Stack for Bulking
SARMs stack for bulking is for the men who are looking for bigger mass and bulking up their entire physique.
One thing about the SARMs stack for bulking is important to note, that it required Post Cycle Therapy, unlike the Cutting Stack.
With the bulking stack of SARMs, you will notice a considerable amount of the energy improvements and see bigger muscle-related improvements popping up. This will power up the exercise timings and lets you work out for more extensive results.
The best SARMs Stack for Bulking includes Testolone and Ligandrol in 15mg of doses daily for 2 months. After this, users have to take a 4-week gap and PCT.
For the strength seekers, using YK11 with Ligandrol is the heavy choice that benefits the weight lifting ability for rapid gains.
This stack can be good for 6 weeks where the dose of Ligandrol should be at 20mg while YK-11 at 10mg per day.
2) SARMs Stack for Cutting
SARMs were created to treat the muscle-wasting disease like in the case of the cancer patients where it beholds the lean mass breakage.
In this way, you can say the role of SARMs stack for cutting is very much neat and effective during the cutting phase.
This cutting phase demands the preservation of lean mass while reducing the fat tissues available on the upper layer of the muscles. And there is nothing better than SARMs in combination doing it.
The effective SARMs stack for cutting should only involve 2 compounds for a strict period of 10 weeks. They should be:
- Cardarine 10mg daily
- Ostarine 20mg daily
There is no need for PCT in the cutting stack, but users need to take a 4-week break which is sort of a recovery phase.
SARMs Cycle Side Effects
It is not true when people say SARMs are devoid of side effects, unlike the anabolic steroids.
In reality, these research chemicals are toxic as the next guy available in shaded sites. Some of the SARMs are halted by the Pharmaceuticals after being developed and this happened for serious reasons.
This would only mean that during the research phase, either these chemicals have shown mysterious effects on human biology or the short term benefits await the long term health complications.
Here are the side effects you can have from doing a whole SARMs cycle.
- Cardiovascular events: Heart Attack and Stroke
- Reduced Good Type of Cholesterol (HDL)
- Vision Problems
- Liver Damage
SARMs Results – What Should You Expect?
SARMs results come in many forms, depends on which SARMs you have chosen for specific bodybuilding goals.
You are ought to get ripped muscle mass, bulkiness with extra strength and energy gains you’ve never noticed before.
Users of SARMs after the whole cycle witnessed the increased rate of muscle mass synthesis and reduction of fat mass around the body, all these effects comes without the water retention and without halting the body shape in any way.
This can be the most attractive part of the SARMs that made thousands of men using them for extra mass on their bones.
For some people, losing fat is pretty difficult, this is the type of result SARMs can deliver, which are used for treating obesity in some men.
These men have bodies storing fats for which SARMs induces the metabolism enhancement without starting the catabolic activity.
Other types of SARMs are used for overcoming muscle fatigue, muscle soreness and to boost the endurance level in athletes.
About SARMs Post Cycle Therapy
The majority of SARMs in low doses do not affect the testosterone level in men, the higher doses on the other hand used by the eager bodybuilders are enough to induce testosterone suppression which can also be resolved by the PCT.
The types of SARMs which cause the suppression effects are Ligandrol and YK-11 (Myostatin).
If you are a heavy Ostarine user who has been taking 25mg per day dosage. You need to perform Post Cycle Therapy, the higher dose of Ostarine leads to testosterone suppression in real.
Now, as the PCT concerns, running a cycle with Nolvadex of around 4 weeks is enough for men to regain their sex hormones. Female users who use SARMs are not allowed to take PCT supplements as they don’t cause testosterone suppression in them.
Note: Always take a 4-week gap between SARMs cycles to avoid T-Level Suppression.
SARMs for Women – Which SARMs Should Women Use
Most female bodybuilders are interested in cutting or endurance to gain the use of SARMs.
For these purposes, using Ligandrol and Andarine is useful for women to help with their muscle tone improvements and achieve an intense endurance level they can work out for hours.
Even the smaller dose for a female is enough i.e. 5 mg daily.
Selective Androgen Receptor Modulators are undoubtedly safer than Anabolic Steroids and Prohormones, but it certainly does not make them safer like OTC medications.
The finest quality of SARMs can be purchased through multiple online pages and if you are interested to do check the quality before attempting your first SARMs Purchase.
Matus Valent at first built up his physique and then a career as a fitness model. He is an athlete and an entrepreneur. His first love was volleyball and eventually, he moved on and started lifting weights.